InterPro domain: IPR005197

O-Glycosyl hydrolases ( 3.2.1. ) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [ 1 , 2 ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.

This is a family of alpha-1,3-glucanases belonging to glycoside hydrolase family 71 ( GH71 ). Endo-1,3-alpha-glucanase Agn1 hydrolyses septum-edging material and acts in concert with endo-(1,3)-beta-glucanase Eng1 to achieve efficient cell separation in fission-yeast [ 3 ].

1. Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases. Proc. Natl. Acad. Sci. U.S.A. 92, 7090-4
2. Structures and mechanisms of glycosyl hydrolases. Structure 3, 853-9
3. Role of the alpha-glucanase Agn1p in fission-yeast cell separation. Mol. Biol. Cell 15, 3903-14