InterPro domain: IPR005174

General Information

  • Identifier IPR005174
  • Description Domain unknown function DUF295
  • Number of genes 3545
  • Gene duplication stats Loading...

Abstract

This domain is found in plant proteins, many of which also contain an F-box domain [ 1 ]. This domain can be found in KIB3 from Arabidopsis. KIB3 is a F-box E3 ubiquitin ligase that promotes the degradation of GSK3-like kinase BIN2 while blocking its substrate access [ 2 ].


1. Neofunctionalization of Mitochondrial Proteins and Incorporation into Signaling Networks in Plants. Mol Biol Evol 36, 974-989
2. The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis. Mol. Cell 66, 648-657.e4

Species distribution

Gene table

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