InterPro domain: IPR005147
General Information
- Identifier IPR005147
- Description tRNA synthetase, B5-domain
- Number of genes 138
- Gene duplication stats Loading...
- Associated GO terms GO:0000287 GO:0005524 GO:0003723 GO:0006432
Abstract
Domain B5 is found in phenylalanine-tRNA synthetase beta subunits. This domain has been shown to bind DNA through a winged helix-turn-helix motif [ 1 ]. Phenylalanine-tRNA synthetase may influence common cellular processes via DNA binding, in addition to its aminoacylation function.
1. DNA-binding of phenylalanyl-tRNA synthetase is accompanied by loop formation of the double-stranded DNA. J. Mol. Biol. 305, 451-8
Species distribution
Gene table
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