InterPro domain: IPR005135
General Information
- Identifier IPR005135
- Description Endonuclease/exonuclease/phosphatase
- Number of genes 3852
- Gene duplication stats Loading...
- Associated GO terms GO:0003824
Abstract
This domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling [ 1 ]. Proteins this domain is found in include: AP endonuclease proteins ( 4.2.99.18 ), DNase I proteins ( 3.1.21.1 ), Synaptojanin an inositol-1,4,5-trisphosphate phosphatase ( 3.1.3.56 ) and Sphingomyelinase ( 3.1.4.12 ).
1. Functionally unrelated signalling proteins contain a fold similar to Mg2+-dependent endonucleases. Trends Biochem. Sci. 25, 272-3
Species distribution
Gene table
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