InterPro domain: IPR005019
General Information
- Identifier IPR005019
- Description Methyladenine glycosylase
- Number of genes 681
- Gene duplication stats Loading...
- Associated GO terms GO:0008725 GO:0006284
Abstract
This family of methyladenine glycosylases includes DNA-3-methyladenine glycosylase I ( 3.2.2.20 ) which acts as a base excision repair enzyme by severing the glycosylic bondof numerous damaged bases. The enzyme is constitutively expressed and is specific for the alkylated 3-methyladenine DNA [ 1 ].
1. Purification and structure of 3-methyladenine-DNA glycosylase I of Escherichia coli. J. Biol. Chem. 261, 15761-6
Species distribution
Gene table
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