InterPro domain: IPR005019

General Information

  • Identifier IPR005019
  • Description Methyladenine glycosylase
  • Number of genes 681
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008725   GO:0006284  

Abstract

This family of methyladenine glycosylases includes DNA-3-methyladenine glycosylase I ( 3.2.2.20 ) which acts as a base excision repair enzyme by severing the glycosylic bondof numerous damaged bases. The enzyme is constitutively expressed and is specific for the alkylated 3-methyladenine DNA [ 1 ].


1. Purification and structure of 3-methyladenine-DNA glycosylase I of Escherichia coli. J. Biol. Chem. 261, 15761-6

Species distribution

Gene table