InterPro domain: IPR005002

General Information

  • Identifier IPR005002
  • Description Phosphomannomutase
  • Number of genes 189
  • Gene duplication stats Loading...
  • Associated GO terms GO:0004615   GO:0009298  

Abstract

This enzyme ( 5.4.2.8 ) is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions [ 1 ].


1. The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a. J. Biol. Chem. 281, 14918-26

Species distribution

Gene table

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