InterPro domain: IPR004823

General Information

  • Identifier IPR004823
  • Description TATA box binding protein associated factor (TAF)
  • Number of genes 216
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006352  

Abstract

The TATA box binding protein associated factor (TAF) is part of the transcription initiation factor TFIID multimeric protein complex. TFIID plays a central role in mediating promoter responses to various activators and repressors. It binds tightly to TAFII-250 and directly interacts with TAFII-40. TFIID is composed of TATA binding protein (TBP)and a number of TBP-associated factors (TAFS). TAF proteins adopt a histone-like fold.

Species distribution

Gene table