InterPro domain: IPR004821

General Information

  • Identifier IPR004821
  • Description Cytidyltransferase-like domain
  • Number of genes 940
  • Gene duplication stats Loading...
  • Associated GO terms GO:0003824   GO:0009058  

Abstract

Protein families that contain at least one copy of this domain include citrate lyase ligase, pantoate-beta-alanine ligase, glycerol-3-phosphate cytidyltransferase [ 1 ], ADP-heptose synthase, phosphocholine cytidylyltransferase, lipopolysaccharide core biosynthesis protein KdtB, the bifunctional protein NadR, archaeal FAD synthase RibL [ 2 ], and a number whose function is unknown. Many of these proteins are known to use CTP or ATP and release pyrophosphate.


1. Crystal structure of CTP:glycerol-3-phosphate cytidylyltransferase from Staphylococcus aureus: examination of structural basis for kinetic mechanism. Biochim. Biophys. Acta 1764, 63-9
2. Archaeal RibL: a new FAD synthetase that is air sensitive. Biochemistry 49, 8748-55

Species distribution

Gene table