InterPro domain: IPR004806

General Information

  • Identifier IPR004806
  • Description UV excision repair protein Rad23
  • Number of genes 456
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006289  

Abstract

All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. Rad23 contains a ubiquitin-like domain that interacts with catalytically active proteasomes and two ubiquitin (Ub)-associated (UBA) sequences that bind Ub. Rad23 interacts with ubiquitinated cellular proteins through the synergistic action of its UBA domains.

In humans, Rad23 complexes with the XPC protein.

Species distribution

Gene table