InterPro domain: IPR004609

General Information

  • Identifier IPR004609
  • Description ATP-dependent DNA helicase RecG

Abstract

The ATP-dependent DNA helicase RecG 3.6.1 plays a critical role in recombination and DNA repair. It helps to process Holliday junction intermediates to mature products by catalysing branch migration. RecG has DNA unwinding activity characteristic of a DNA helicase with 3' to 5' polarity. RecG unwind branched duplex DNA (Y-DNA) and has a role in constitutive stable DNA replication (CsdR) and R-loop formation [ 1 , 2 ].


1. Branch migration of Holliday junctions: identification of RecG protein as a junction specific DNA helicase. EMBO J. 13, 5220-8
2. Escherichia coli RecG and RecA proteins in R-loop formation. EMBO J. 14, 2385-92

Species distribution

Gene table