InterPro domain: IPR004600

General Information

  • Identifier IPR004600
  • Description TFIIH subunit Tfb4/GTF2H3

Abstract

This entry represents Tfb4/GTF2H3, a component of the transcription factor TFIIH core (includes XPB, p62, p52, p44, p34). TFIIH complex is involved in the nucleotide excision repair (NER) and polymerase II transcription [ 1 , 2 , 3 ].


1. RNA polymerase transcription factor IIH holoenzyme from yeast. J. Biol. Chem. 269, 28044-8
2. Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair. J. Biol. Chem. 271, 10821-6
3. The TFB4 subunit of yeast TFIIH is required for both nucleotide excision repair and RNA polymerase II transcription. J. Biol. Chem. 274, 29564-7

Species distribution

Gene table