InterPro domain: IPR004396

Ribosome-binding ATPase YchF is a yeast ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner [ 1 ]. The mammalian homologue of YchF has been termed OLA1, for Obg-like ATPase 1 [ 2 ]. These proteins bind and hydrolyse ATP more efficiently than GTP, therefore their name. ATPase activity is a general feature of the YchF subfamily of Obg-like GTPases [ 3 ].

1. Deciphering the catalytic machinery in a universally conserved ribosome binding ATPase YchF. Biochem. Biophys. Res. Commun. 408, 459-64
2. Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins. J. Biol. Chem. 282, 19928-37