InterPro domain: IPR004324

This entry includes folate-biopterin transporters (FBTs) from blue-green algae and plants, including Slr0642 protein from Synechocystis and its plastidial orthologue At2g32040 from Arabidopsis [ 1 ]. Both Slr0642 protein and At2g32040 mediate folate monoglutamate transport involved in tetrahydrofolate biosynthesis. However, this entry also includes 7 other Arabidopsis FBT proteins that lack conserved critical residues and may not have folate or pterin transport activity [ 2 ].

1. Identification of transport-critical residues in a folate transporter from the folate-biopterin transporter (FBT) family. J. Biol. Chem. 285, 2867-75