InterPro domain: IPR003874

General Information

  • Identifier IPR003874
  • Description CDC45 family
  • Number of genes 150
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006270  

Abstract

CDC45 is an essential gene required for initiation of DNA replication in Saccharomyces cerevisiae (cell division control protein 45), forming a complex with MCM5/CDC46. Homologs of CDC45 have been identified in human [ 1 ], mouse and the smut fungus, Melampsora spp., (tsd2 protein) among others.


1. The human homolog of Saccharomyces cerevisiae CDC45. J. Biol. Chem. 273, 18205-9

Species distribution

Gene table