InterPro domain: IPR003758
General Information
- Identifier IPR003758
- Description Tetraacyldisaccharide 4'-kinase
- Number of genes 111
- Gene duplication stats Loading...
- Associated GO terms GO:0005524 GO:0009245 GO:0009029
Abstract
Tetraacyldisaccharide 4'-kinase phosphorylates the 4'-position of a tetraacyldisaccharide 1-phosphate precursor (DS-1-P) of lipid A, but the enzyme has not yet been purified because of instability [ 1 ]. This enzyme is involved in the synthesis of lipid A portion of the bacterial lipopolysaccharide layer (LPS).
1. Accumulation of a lipid A precursor lacking the 4'-phosphate following inactivation of the Escherichia coli lpxK gene. J. Biol. Chem. 273, 12457-65
Species distribution
Gene table
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