InterPro domain: IPR003611

General Information

  • Identifier IPR003611
  • Description Nuclease associated modular domain 3
  • Number of genes 252
  • Gene duplication stats Loading...
  • Associated GO terms GO:0003677  

Abstract

NUMOD3 (nuclease associated modular domain 3) is a DNA-binding motif found in homing endonucleases and related proteins. It occurs on its own or in tandem repeats in GIY-YIG and HTH proteins. It constitutes a beta-turn-loop-helix subregion of the the DNA-binding domain of I-TevI homing endonuclease ( P13299 ) [ 1 ].


1. New types of conserved sequence domains in DNA-binding regions of homing endonucleases. Trends Biochem. Sci. 28, 473-7

Species distribution

Gene table