InterPro domain: IPR003544
General Information
- Identifier IPR003544
- Description Cytochrome c-type biogenesis protein CcmB
- Number of genes 56
- Gene duplication stats Loading...
- Associated GO terms GO:0015232 GO:0016020 GO:0017004 GO:0015886
Abstract
This entry represents cytochrome c-type biogenesis protein CcmB (HelB) from bacteria and plants.
CcmB is the product of one of a cluster of ccm genes that are necessary for cytochrome c biosynthesis in bacteria and is required for the export of haem to the periplasm [ 1 ]. Plant mitochondria have kept a cytochrome c biogenesis pathway inherited from their prokaryote ancestor and also have a CcmB homologue, but in plants the ccm genes are distributed between the nuclear and the mitochondrial genomes instead of being coded in a single operon [ 2 , 3 ].
1. Escherichia coli genes required for cytochrome c maturation. J. Bacteriol. 177, 4321-6
2. Wheat mitochondria ccmB encodes the membrane domain of a putative ABC transporter involved in cytochrome c biogenesis. Biochim. Biophys. Acta 1519, 199-208
3. Cytochrome c biogenesis in mitochondria. Mitochondrion 8, 61-73