InterPro domain: IPR002755

General Information

  • Identifier IPR002755
  • Description DNA primase, small subunit
  • Number of genes 153
  • Gene duplication stats Loading...
  • Associated GO terms GO:0003896   GO:0006269  

Abstract

This family represents the small subunit, and also includes baculovirus late expression factor 1 or LEF-1 proteins. Baculovirus LEF-1 is a DNA primase enzyme [ 1 ].

DNA primase synthesises the RNA primers for the Okazaki fragments in lagging strand DNA synthesis. DNA primase is a heterodimer of large and small subunits [ 2 ].


1. Baculovirus replication factor LEF-1 is a DNA primase. J. Virol. 76, 2287-97
2. Mutations in conserved yeast DNA primase domains impair DNA replication in vivo. Proc. Natl. Acad. Sci. U.S.A. 88, 3877-81

Species distribution

Gene table