InterPro domain: IPR002734

General Information

  • Identifier IPR002734
  • Description Bacterial bifunctional deaminase-reductase, C-terminal
  • Number of genes 160
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008703   GO:0009231  

Abstract

This domain isfound in the C terminus of the bifunctional deaminase-reductase of Escherichia coli, Bacillus subtilis and other bacteria in combination with IPR002125 that catalyses the second and third steps in the biosynthesis of riboflavin, i.e., the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (deaminase) and the subsequent reduction of the ribosyl side chain (reductase) [ 1 ]. The domain is also present in some HTP reductases from archaea and fungi.


1. Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis. J. Bacteriol. 179, 2022-8

Species distribution

Gene table