InterPro domain: IPR002585
General Information
- Identifier IPR002585
- Description Cytochrome ubiquinol oxidase subunit 1
- Number of genes 2
- Gene duplication stats Loading...
- Associated GO terms GO:0009055 GO:0070069 GO:0019646
Abstract
This family are the alternative oxidases found in many bacteria which oxidise ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase. E. coli has two copies of the oxidase, bo and bd. Only bd is represented here In some nitrogen fixing bacteria.
Cytochrome bd may play an important role in microaerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae, where it is expressed under all conditions that permit diazotrophy [ 1 ]. Subunit I binds a single b-haem, through ligands at His186 and Met393 (using P0ABJ9 numbering). In addition His19 is a ligand for the haem b found in subunit II ( IPR003317 ).
1. The Klebsiella pneumoniae cytochrome bd' terminal oxidase complex and its role in microaerobic nitrogen fixation. Microbiology (Reading, Engl.) 143 ( Pt 8), 2673-83