InterPro domain: IPR001207
General Information
- Identifier IPR001207
- Description Transposase, mutator type
- Number of genes 55
- Gene duplication stats Loading...
- Associated GO terms GO:0003677 GO:0004803 GO:0006313
Abstract
Autonomous mobile genetic elements such as transposon or insertion sequences (IS) encode an enzyme, transposase, that is required for excising and insertingthe mobile element. Transposases have been grouped into various families [ 1 , 2 , 3 ]. The mutator family of transposases consists of a number of elements that include, mutator from maize, IsT2 from Thiobacillus ferrooxidans, Is256 from Staphylococcus aureus, Is1201 from Lactobacillus helveticus, Is1081 from Mycobacterium bovis, IsRm3 from Rhizobium melilotiand others.
1. Sequence similarity of putative transposases links the maize Mutator autonomous element and a group of bacterial insertion sequences. Nucleic Acids Res. 22, 2634-6
2. Isolation and analysis of IS6120, a new insertion sequence from Mycobacterium smegmatis. Mol. Microbiol. 6, 107-13
3. IS406 and IS407, two gene-activating insertion sequences for Pseudomonas cepacia. Gene 105, 101-5