InterPro domain: IPR000689

General Information

  • Identifier IPR000689
  • Description Ubiquinone biosynthesis monooxygenase COQ6
  • Number of genes 56
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008681   GO:0006744  

Abstract

Ubiquinone (Q) functions as an electron carrier in the respiratory chain in mitochondria. Q biosynthesis involves a series of enzymatic steps, which are catalysed by the enzymes COQ1-COQ8 in Saccharomyces cerevisiae (Baker's yeast). COQ6, or ubiquinone biosynthesis monooxygenase, is a flavin-dependent enzyme localised to the matrix side of the inner mitochondrial membrane that is required for one or more steps in Q biosynthesis [ 1 , 2 ].


1. Ubiquinone biosynthesis in microorganisms. FEMS Microbiol. Lett. 203, 131-9
2. The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis. J. Biol. Chem. 278, 25308-16

Species distribution

Gene table