InterPro domain: IPR000526

Auxin binding protein is located in the lumen of the endoplasmic reticulum (ER). The primary structure contains an N-terminal hydrophobic leader sequence of 30-40 amino acids, which could represent a signal for translocation of the protein to the ER [ 1 , 2 ]. The mature protein comprises around 165 residues, and contains a number of potential N-glycosylation sites. In vitro transport studies have demonstrated co-translational glycosylation [ 3 ]. Retention within the lumen of the ER correlates withan additional signal located at the C terminus, represented by the sequence Lys-Asp-Glu-Leu, known to be responsible for preventing secretion of proteins from the lumen of the ER in eukaryotic cells [ 3 , 3 ].

1. Molecular cloning and structural analysis of a gene from Zea mays (L.) coding for a putative receptor for the plant hormone auxin. EMBO J. 8, 2453-61
2. Molecular analysis of an auxin binding protein gene located on chromosome 4 of Arabidopsis. Plant Cell 4, 193-201