InterPro domain: IPR000415

This domain superfamily is characteristic of nitroreductase enzymes and related oxidoreductases.Members of this family utilise FMN as a cofactor and areoften found to be homodimers. Possible characteristics include Oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) ( 1.6.99.7 ) and NADH dehydrogenase ( 1.6.99.3 ). A number of the proteins are described as oxidoreductases. They are primarily found in bacterial lineages though a number of eukaryotic homologues have been identified: Caenorhabditis elegans P34273 , Drosophila melanogaster (Fruit fly) Q8T3Q0 Q9VTE7 , Mus musculus (Mouse) Q9DCX8 and Homo sapiens (Human) O75989 . This protein is not found in photosynthetic eukaryotes. The sequences containing this entry in photosynthetic organisms are possible false positives.