InterPro domain: IPR000109
General Information
- Identifier IPR000109
- Description Proton-dependent oligopeptide transporter family
- Number of genes 7879
- Gene duplication stats Loading...
- Associated GO terms GO:0055085 GO:0022857 GO:0016020
Abstract
The proton-dependent oligopeptide transporter (POT) family (also known as the peptide transport (PTR) family) is made up of a group of energy-dependent transporters found in organisms as diverse as bacteria and humans. The POT family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of peptide transport proteins [ 1 ]. They seem to be mainly involved in the intake of small peptides [ 2 ]. However, some family members are nitrate permeases and others are involved in histidine transport [ 3 ].
1. The PTR family: a new group of peptide transporters. Mol. Microbiol. 16, 825-34
2. The POT family of transport proteins. Trends Biochem. Sci. 19, 404
3. Nitrate transporters and peptide transporters. FEBS Lett. 581, 2290-300