Gene: Sopen12g033680

General Information

Structural Information

  • Species Solanum pennellii
  • Gene Identifier Sopen12g033680
  • Transcript Identifier Sopen12g033680.1
  • Gene Type Coding gene
  • Location Spenn-ch12 : 82210725-82212936 : negative

Gene Family Information

  • ID HOM05D003727
  • #Genes/#Species 185/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid Sopen12g033680.1

Descriptions

  • Description Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1, #945 | subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily. | pyruvate dehydrogenase kinase (PDK) | FUNCTIONS IN: ATP binding, pyruvate dehydrogenase (acetyl-transferring) kinase activity, histidine phosphotransfer kinase activity | INVOLVED IN: signal transduction, peptidyl-histidine phosphorylation, phosphorylation | LOCATED IN: mitochondrion | EXPRESSED IN: 24 plant structures | EXPRESSED DURING: 15 growth stages | CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, core , Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, mitochondrial , ATPase-like, ATP-binding domain , Signal transduction histidine kinase-related protein, C-terminal
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043086
ISO
PLAZA Integrative Orthologynegative regulation of catalytic activity Zm00001eb328730
GO:0046777
ISO
PLAZA Integrative Orthologyprotein autophosphorylation AT3G06483
GO:0016310
ISO
PLAZA Homology (enrichment)phosphorylation HOM05D003727

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004672
IEA
InterProprotein kinase activity
GO:0009927
ISO
PLAZA Integrative Orthologyhistidine phosphotransfer kinase activity AT3G06483
GO:0005524
ISO
PLAZA Integrative OrthologyATP binding Zm00001eb328730
GO:0042803
ISO
PLAZA Integrative Orthologyprotein homodimerization activity AT3G06483
GO:0016772
ISO
PLAZA Homology (enrichment)transferase activity, transferring phosphorus-containing groups HOM05D003727
GO:0004740
ISO
PLAZA Integrative Orthologypyruvate dehydrogenase (acetyl-transferring) kinase activity Zm00001eb328730

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005759
ISO
PLAZA Integrative Orthologymitochondrial matrix Zm00001eb328730

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036890 Histidine kinase/HSP90-like ATPase superfamily
IPR003594 Histidine kinase/HSP90-like ATPase
IPR039028 PDK/BCKDK protein kinase
IPR018955 Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
IPR036784 Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily
Mapman id Description
2.2.1.4.1 Cellular respiration.pyruvate oxidation.mitochondrial pyruvate dehydrogenase complex.regulation.pyruvate dehydrogenase kinase