Gene: Sopen10g025390

General Information

Description SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif. | S phase kinase-associated protein 1 (SKP1) | FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding | INVOLVED IN: negative regulation of DNA recombination, response to cadmium ion, mitosis, male meiosis, ubiquitin-dependent protein catabolic process | LOCATED IN: in 7 components | EXPRESSED IN: 35 plant structures | EXPRESSED DURING: 15 growth stages | CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit , SKP1 component, dimerisation , SKP1 component , BTB/POZ fold , SKP1 component, POZ | BEST Arabidopsis thaliana protein match is: E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0006511	IEA	InterPro	ubiquitin-dependent protein catabolic process

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR016897	S-phase kinase-associated protein 1
IPR011333	SKP1/BTB/POZ domain superfamily
IPR016072	SKP1 component, dimerisation
IPR001232	S-phase kinase-associated protein 1-like
IPR016073	SKP1 component, POZ domain
IPR036296	SKP1-like, dimerisation domain superfamily

Mapman id	Description
19.2.2.8.1.2	Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ubiquitin ligase complexes.target protein binding component SKP1/ASK1