Gene: Sopen04g007420

General Information

Description Phosphatidylinositol 3-kinase, root isoform (EC 2.7.1.137) (PI3-kinase) (PtdIns-3-kinase) (PI3K) (SPI3K-5) - Glycine max (Soybean), Encodes a phosphatidylinositol 3-kinase that is expressed in most plant tissues. Defects in VPS34 affect a number of cellular processes. Loss of function mutations are not transmitted through the male gametophyte due to defects in microgametogenesis therefore it is difficult to assess the effects of loss of VPS34 function in the whole plant. Involved in salt-stress responses. | vacuolar protein sorting 34 (VPS34) | FUNCTIONS IN: 1-phosphatidylinositol-3-kinase activity, inositol or phosphatidylinositol kinase activity, binding, phosphotransferase activity, alcohol group as acceptor | INVOLVED IN: oxygen and reactive oxygen species metabolic process, response to salt stress, endocytosis, N-terminal protein myristoylation, microgametogenesis | LOCATED IN: phosphoinositide 3-kinase complex | EXPRESSED IN: 23 plant structures | EXPRESSED DURING: 13 growth stages | CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic , Phosphoinositide 3-kinase, accessory (PIK) domain , Phosphoinositide 3-kinase, C2 , C2 calcium/lipid-binding domain, CaLB , Protein kinase-like domain , Phosphatidylinositol Kinase , Phosphatidylinositol 3-kinase, Vps34 type , Armadillo-type fold , Phosphatidylinositol 3/4-kinase, conserved site | BEST Arabidopsis thaliana protein match is: Phosphatidylinositol 3- and 4-kinase family protein

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0046854	IEA	InterPro	phosphatidylinositol phosphate biosynthetic process
GO:0048015	IEA	InterPro	phosphatidylinositol-mediated signaling
GO:0072593	ISO	PLAZA Integrative Orthology	reactive oxygen species metabolic process	AT1G60490
GO:0009651	ISO	PLAZA Integrative Orthology	response to salt stress	AT1G60490
GO:0055046	ISO	PLAZA Integrative Orthology	microgametogenesis	AT1G60490
GO:0006897	ISO	PLAZA Integrative Orthology	endocytosis	AT1G60490

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0016303	IEA	InterPro	1-phosphatidylinositol-3-kinase activity
GO:0016301	IEA	InterPro	kinase activity
GO:0005515	ISO	PLAZA Integrative Orthology	protein binding	AT1G60490

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR008290	Phosphatidylinositol 3-kinase, Vps34 type
IPR002420	C2 phosphatidylinositol 3-kinase-type domain
IPR035892	C2 domain superfamily
IPR001263	Phosphoinositide 3-kinase, accessory (PIK) domain
IPR016024	Armadillo-type fold
IPR000403	Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR011009	Protein kinase-like domain superfamily
IPR011162	MHC classes I/II-like antigen recognition protein
IPR036940	Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
IPR015433	Phosphatidylinositol kinase
IPR042236	Phosphoinositide 3-kinase, accessory (PIK) domain superfamily

Mapman id	Description
19.3.2.1	Protein homeostasis.autophagy.nucleation complexes.phosphatidylinositol 3-kinase component VPS34/PI3K
27.5.1.4.1	Multi-process regulation.phosphatidylinositol and inositol phosphate system.biosynthesis.phosphatidylinositol kinase activities.phosphatidylinositol 3-kinase (VPS34)