Gene: Sopen03g032020
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen03g032020
- Transcript Identifier Sopen03g032020.1
- Gene Type Coding gene
- Location Spenn-ch03 : 67541167-67594240 : positive
Gene Family Information
- ID HOM05D001734
- #Genes/#Species 373/100
- Phylogenetic origin
- ID ORTHO05D003483
- #Genes/#Species 221/98
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid Sopen03g032020.1
Descriptions
- Description encodes a homolog of the human ATM gene, which is mutated in ataxia telangiectasia, a chromosome instability disorder. Characterization of mutants suggest a role in repairing DNA in response to ionizing radiation as well as during meiosis. The protein has kinase domains and shows kinase activity in orthologs. There is also evidence that ATM might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres. | ataxia-telangiectasia mutated (ATM) | FUNCTIONS IN: 1-phosphatidylinositol-3-phosphate 5-kinase activity | INVOLVED IN: in 8 processes | LOCATED IN: chloroplast | EXPRESSED IN: 26 plant structures | EXPRESSED DURING: 13 growth stages | CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic , PIK-related kinase, FAT , Ataxia-Telangiectasia Mutated , PIK-related kinase , PWWP , PIK-related kinase, FATC , Phosphatidylinositol 3/4-kinase, conserved site , Protein kinase-like domain | BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0045003 | ISO | PLAZA Integrative Orthology | double-strand break repair via synthesis-dependent strand annealing | AT3G48190 |
GO:0032204 | ISO | PLAZA Integrative Orthology | regulation of telomere maintenance | AT3G48190 |
GO:0010212 | ISO | PLAZA Integrative Orthology | response to ionizing radiation | AT3G48190 |
GO:0010332 | ISO | PLAZA Integrative Orthology | response to gamma radiation | AT3G48190 |
GO:0032504 | ISO | PLAZA Integrative Orthology | multicellular organism reproduction | AT3G48190 |
GO:0051321 | ISO | PLAZA Integrative Orthology | meiotic cell cycle | AT3G48190 |
GO:0007129 | ISO | PLAZA Integrative Orthology | homologous chromosome pairing at meiosis | AT3G48190 |
GO:0043247 | ISO | PLAZA Integrative Orthology | telomere maintenance in response to DNA damage | AT3G48190 |
GO:0006303 | ISO | PLAZA Integrative Orthology | double-strand break repair via nonhomologous end joining | AT3G48190 |
GO:0033044 | ISO | PLAZA Integrative Orthology | regulation of chromosome organization | AT3G48190 |
GO:0007131 | ISO | PLAZA Integrative Orthology | reciprocal meiotic recombination | AT3G48190 |
GO:0008380 | ISO | PLAZA Integrative Orthology | RNA splicing | AT3G48190 |
GO:2001020 | ISO | PLAZA Integrative Orthology | regulation of response to DNA damage stimulus | AT3G48190 |
GO:0006281 | IEA | InterPro | DNA repair | |
GO:0006974 | IEA | InterPro | cellular response to DNA damage stimulus |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0000285 | ISO | PLAZA Integrative Orthology | 1-phosphatidylinositol-3-phosphate 5-kinase activity | AT3G48190 |
GO:0005515 | IEA | InterPro | protein binding | |
GO:0016301 | IEA | InterPro | kinase activity | |
GO:0004674 | IEA | InterPro | protein serine/threonine kinase activity |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR011009 | Protein kinase-like domain superfamily |
IPR003152 | FATC domain |
IPR021668 | Telomere-length maintenance and DNA damage repair |
IPR000403 | Phosphatidylinositol 3-/4-kinase, catalytic domain |
IPR038980 | Serine/threonine-protein kinase ATM, plant |
IPR016024 | Armadillo-type fold |
IPR044107 | ATM, catalytic domain |
IPR036940 | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily |
Mapman id | Description |
---|---|
14.1.1 | DNA damage response.DNA damage sensing and signalling.DNA double-strand break response kinase (ATM) |