Gene: Sopen02g030080

General Information

Description Protein is similar to SWI2/SNF2 chromatin remodeling proteins. DDM1 is appears to act as a chromatin-remodeling ATPase involved in cytosine methylation in CG and non-CG contexts. Involved in gene silencing and maintenance of DNA methylation and histone methylation. Hypomethylation of many genomic regions occurs in ddm1 mutants, and can cause several phenotypic abnormalities, but some loci, such as BONSAI (At1g73177) can be hypermethylated in ddm1 mutants after several generations, leading to different phenotypes. DDM1 might be involved in establishing a heterochromain boundary. A line expressing an RNAi targeted against DDM1 shows some resistance to agrobacterium-mediated root transformation. | chromatin remodeling 1 (CHR1) | FUNCTIONS IN: helicase activity, ATPase activity | INVOLVED IN: methylation-dependent chromatin silencing, DNA mediated transformation, transposition, RNA-mediated | LOCATED IN: nucleosome | EXPRESSED IN: 21 plant structures | EXPRESSED DURING: 14 growth stages | CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal , DNA/RNA helicase, C-terminal , Helicase, superfamily 1/2, ATP-binding domain , SNF2-related | BEST Arabidopsis thaliana protein match is: chromatin remodeling factor17

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005524	IEA	InterPro	ATP binding
GO:0070615	IEA	InterPro	nucleosome-dependent ATPase activity

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR001650	Helicase, C-terminal
IPR014001	Helicase superfamily 1/2, ATP-binding domain
IPR000330	SNF2, N-terminal
IPR038718	SNF2-like, N-terminal domain superfamily

Mapman id	Description
12.5.2.1	Chromatin organisation.DNA methylation.RNA-independent DNA methylation.chromatin remodeling factor (DDM1)