Gene: Cre02.g078858

General Information

Structural Information

  • Species Chlamydomonas reinhardtii
  • Gene Identifier Cre02.g078858
  • Transcript Identifier Cre02.g078858.t1.1
  • Gene Type Coding gene
  • Location chromosome_2 : 784982-790297 : positive

Gene Family Information

  • ID HOM05D002946
  • #Genes/#Species 234/98
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • id Cre02.g078858.v5.5
  • pacid 30786287
  • alias g1433.t1
  • geneName PSN1
  • uniprot A8IAG6

Descriptions

  • Description Aspartic protease (A22 family), catalytic subunit of the gamma-secretase complex; carries out intramembrane cleavage of type I monotopic membrane proteins like beta-Amyloid Precursor Protein (PMID: 17047369); presenilin is activated by cleavage in the non
  • Description Presenilin protease
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016485
IEA
GOA Databaseprotein processing
GO:0016485
IEA
InterProprotein processing
GO:0007219
IEA
GOA DatabaseNotch signaling pathway
GO:0006508
IEA
GOA Databaseproteolysis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008233
IEA
GOA Databasepeptidase activity
GO:0004190
IEA
GOA Databaseaspartic-type endopeptidase activity
GO:0004190
IEA
InterProaspartic-type endopeptidase activity
GO:0016787
IEA
GOA Databasehydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005798
ISO
PLAZA Integrative OrthologyGolgi-associated vesicle AT1G08700
GO:0043231
ISO
PLAZA Integrative Orthologyintracellular membrane-bounded organelle AT1G08700
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0016021
IEA
InterProintegral component of membrane
GO:0005783
IEA
GOA Databaseendoplasmic reticulum
GO:0005794
IEA
GOA DatabaseGolgi apparatus
GO:0005789
IEA
GOA Databaseendoplasmic reticulum membrane
GO:0000139
IEA
GOA DatabaseGolgi membrane
GO:0016020
IEA
GOA Databasemembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001108 Peptidase A22A, presenilin
IPR006639 Presenilin/signal peptide peptidase
IPR042524 Presenilin, C-terminal
Mapman id Description
18.11.1.5.1 Protein modification.targeting peptide maturation.endomembrane system.gamma secretase complex.catalytic component PS