Gene: AT5G64300

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G64300
  • Transcript Identifier AT5G64300.1
  • Gene Type Coding gene
  • Location Chr5 : 25718459-25720790 : positive

Gene Family Information

  • ID HOM05D000723
  • #Genes/#Species 800/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G64300.1
  • symbol GCH
  • Alias ATGCH,ARABIDOPSIS THALIANA GTP CYCLOHYDROLASE II,ATRIBA1,Arabidopsis thaliana riboflavin A1,RFD1,RED FLUORESCENT IN DARKNESS 1,RIBA1,riboflavin A1
  • uniprot P47924

Descriptions

  • Description GTP cyclohydrolase II
  • Computational description GTP cyclohydrolase II (GCH); FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: riboflavin biosynthesis protein, putative (TAIR:AT2G22450.1); Has 11690 Blast hits to 11688 proteins in 2324 species: Archae - 209; Bacteria - 6956; Metazoa - 1; Fungi - 397; Plants - 132; Viruses - 0; Other Eukaryotes - 3995 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006412
ISO
PLAZA Homology (enrichment)translation HOM05D000723
GO:0009231
IMP, IGI
IBA
IEA
Gene Ontologyriboflavin biosynthetic process1 2 3
GO:0009231
IEA
InterProriboflavin biosynthetic process
GO:0008152
IEA
GOA Databasemetabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003735
ISO
PLAZA Homology (enrichment)structural constituent of ribosome HOM05D000723
GO:0003935
IEA
GOA DatabaseGTP cyclohydrolase II activity
GO:0003935
IDA, IGI
Gene OntologyGTP cyclohydrolase II activity1 3
GO:0003935
IEA
InterProGTP cyclohydrolase II activity
GO:0008686
IEA
GOA Database3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0008686
IDA, IGI
IBA
Gene Ontology3,4-dihydroxy-2-butanone-4-phosphate synthase activity1 2 3
GO:0008686
IEA
InterPro3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0005525
IEA
GOA DatabaseGTP binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016829
IEA
GOA Databaselyase activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0046872
IEA
GOA Databasemetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IEA
GOA Databasechloroplast
GO:0009507
IDA, HDA
ISM, IBA
Gene Ontologychloroplast2 3 4
GO:0005840
ISO
PLAZA Homology (enrichment)ribosome HOM05D000723
GO:0009536
IEA
GOA Databaseplastid
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma5

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB
IPR036144 GTP cyclohydrolase II superfamily
IPR032677 GTP cyclohydrolase II
IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily
IPR000926 GTP cyclohydrolase II, RibA
Mapman id Description
7.10.3 Coenzyme metabolism.FMN/FAD biosynthesis.bifunctional GTP cyclohydrolase II (RibA) and DHBP synthase (RibB)