Gene: AT5G55760

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G55760
  • Transcript Identifier AT5G55760.1
  • Gene Type Coding gene
  • Location Chr5 : 22567282-22570716 : positive

Gene Family Information

  • ID HOM05D004103
  • #Genes/#Species 172/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G55760.1
  • symbol SRT1
  • uniprot Q9FE17

Descriptions

  • Description sirtuin 1
  • Computational description sirtuin 1 (SRT1); FUNCTIONS IN: NAD binding, DNA binding, zinc ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: protein amino acid deacetylation, chromatin silencing, regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: chromatin silencing complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent histone deacetylase, silent information regulator Sir2 (InterPro:IPR003000); BEST Arabidopsis thaliana protein match is: sirtuin 2 (TAIR:AT5G09230.7); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IBA
Gene Ontologynegative regulation of transcription by RNA polymerase II1
GO:0070932
IBA
Gene Ontologyhistone H3 deacetylation1
GO:0043970
IGI
Gene Ontologyhistone H3-K9 acetylation2
GO:0009873
IGI
Gene Ontologyethylene-activated signaling pathway2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004407
IBA
Gene Ontologyhistone deacetylase activity1
GO:0070403
IEA
Gene OntologyNAD+ binding
GO:0070403
IEA
InterProNAD+ binding
GO:0016740
IEA
GOA Databasetransferase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0019213
IBA
Gene Ontologydeacetylase activity1
GO:0003714
IBA
Gene Ontologytranscription corepressor activity1
GO:0031490
IDA
Gene Ontologychromatin DNA binding3
GO:0005515
IPI
Gene Ontologyprotein binding3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
IBA
Gene Ontologynucleus1 3
GO:0005737
ISM
Gene Ontologycytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR029035 DHS-like NAD/FAD-binding domain superfamily
IPR003000 Sirtuin family
Mapman id Description
12.3.2.3 Chromatin organisation.post-translational histone modification.histone deacetylation.SIRTUIN histone deacetylase