Gene: AT5G55310

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G55310
  • Transcript Identifier AT5G55310.1
  • Gene Type Coding gene
  • Location Chr5 : 22430389-22434590 : negative

Gene Family Information

  • ID HOM05D002795
  • #Genes/#Species 248/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G55310.1
  • symbol TOP1BETA
  • Alias TOP1,TOPOISOMERASE 1
  • uniprot Q9FJ79

Descriptions

  • Description DNA topoisomerase 1 beta
  • Computational description DNA topoisomerase 1 beta (TOP1BETA); FUNCTIONS IN: DNA topoisomerase type I activity; INVOLVED IN: DNA topological change; LOCATED IN: membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type (InterPro:IPR013030), DNA topoisomerase I, DNA binding, eukaryotic-type (InterPro:IPR008336), DNA topoisomerase I, C-terminal (InterPro:IPR001631), DNA topoisomerase I, active site (InterPro:IPR018521), DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type (InterPro:IPR014727), DNA topoisomerase I, catalytic core, eukaryotic-type (InterPro:IPR013500), DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type (InterPro:IPR014711), DNA topoisomerase I, C-terminal, eukaryotic-type (InterPro:IPR013499), DNA breaking-rejoining enzyme, catalytic core (InterPro:IPR011010); BEST Arabidopsis thaliana protein match is: DNA topoisomerase I alpha (TAIR:AT5G55300.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006265
IEA
GOA DatabaseDNA topological change
GO:0006265
IBA
IC
Gene OntologyDNA topological change1 2
GO:0006265
IEA
InterProDNA topological change
GO:0006338
IBA
Gene Ontologychromatin remodeling2
GO:0007059
IBA
Gene Ontologychromosome segregation2
GO:0006260
IBA
Gene OntologyDNA replication2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003917
IEA
GOA DatabaseDNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0003917
ISS, IBA
Gene OntologyDNA topoisomerase type I (single strand cut, ATP-independent) activity1 2
GO:0003917
IEA
InterProDNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0016853
IEA
GOA Databaseisomerase activity
GO:0003916
IEA
GOA DatabaseDNA topoisomerase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus
GO:0005694
IEA
Gene Ontologychromosome
GO:0005694
IEA
InterProchromosome
GO:0005730
IBA
Gene Ontologynucleolus2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type
IPR013030 DNA topoisomerase I, DNA binding, N-terminal domain 2
IPR008336 DNA topoisomerase I, DNA binding, eukaryotic-type
IPR014727 DNA topoisomerase I, catalytic core, alpha/beta subdomain
IPR011010 DNA breaking-rejoining enzyme, catalytic core
IPR036202 DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily
IPR013499 DNA topoisomerase I, eukaryotic-type
IPR025834 Topoisomerase I C-terminal domain
IPR001631 DNA topoisomerase I
IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type
IPR013034 DNA topoisomerase I, DNA binding, N-terminal domain 1
Mapman id Description
13.2.1.5 Cell cycle organisation.DNA replication.preinitiation.DNA topoisomerase (TOP1)