Gene: AT5G46330

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G46330
  • Transcript Identifier AT5G46330.2
  • Gene Type Coding gene
  • Location Chr5 : 18791802-18795407 : positive

Gene Family Information

  • ID HOM05D000021
  • #Genes/#Species 6213/95
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G46330.2
  • symbol FLS2
  • full_name FLAGELLIN-SENSITIVE 2
  • uniprot Q9FL28

Descriptions

  • Description Leucine-rich receptor-like protein kinase family protein
  • Computational description FLAGELLIN-SENSITIVE 2 (FLS2); FUNCTIONS IN: protein serine/threonine kinase activity, transmembrane receptor protein serine/threonine kinase activity, kinase activity, ATP binding; INVOLVED IN: in 6 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase (TAIR:AT4G20140.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016310
IEA
GOA Databasephosphorylation
GO:0006952
IEA
GOA Databasedefense response
GO:0006468
IEA
Gene Ontologyprotein phosphorylation
GO:0006468
IEA
InterProprotein phosphorylation
GO:0016045
IMP
Gene Ontologydetection of bacterium1
GO:0042742
IMP
Gene Ontologydefense response to bacterium2
GO:0052544
IMP
Gene Ontologydefense response by callose deposition in cell wall3
GO:0010359
IMP
Gene Ontologyregulation of anion channel activity4
GO:0006898
IDA
Gene Ontologyreceptor-mediated endocytosis5
GO:0007178
IEA
GOA Databasetransmembrane receptor protein serine/threonine kinase signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016740
IEA
GOA Databasetransferase activity
GO:0004674
IEA
GOA Databaseprotein serine/threonine kinase activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0016301
IEA
GOA Databasekinase activity
GO:0016301
ISS
Gene Ontologykinase activity
GO:0004672
IEA
GOA Databaseprotein kinase activity
GO:0004672
IEA
InterProprotein kinase activity
GO:0005515
IPI
Gene Ontologyprotein binding6
GO:0005515
IEA
InterProprotein binding
GO:0106310
IEA
Gene Ontologyprotein serine kinase activity
GO:0106311
IEA
Gene Ontologyprotein threonine kinase activity
GO:0004675
ISS
Gene Ontologytransmembrane receptor protein serine/threonine kinase activity1
GO:0042802
IPI
Gene Ontologyidentical protein binding7

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IDA
IEA
GOA Databaseplasma membrane
GO:0005886
HDA
ISM, IBA
Gene Ontologyplasma membrane8 9
GO:0005768
IEA
GOA Databaseendosome
GO:0005768
IDA
Gene Ontologyendosome5
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0016020
IEA
GOA Databasemembrane
GO:0016020
IDA
ISS
Gene Ontologymembrane1 10
GO:0010008
IEA
GOA Databaseendosome membrane
GO:0012505
IDA
GOA Databaseendomembrane system

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR032675 Leucine-rich repeat domain superfamily
IPR013210 Leucine-rich repeat-containing N-terminal, plant-type
IPR011009 Protein kinase-like domain superfamily
IPR000719 Protein kinase domain
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
Mapman id Description
18.4.1.12 Protein modification.phosphorylation.TKL protein kinase superfamily.protein kinase (LRR-XII)
26.9.1.1.1.1 External stimuli response.pathogen.pattern-triggered immunity (PTI) network.bacterial elicitor response.FLS2-BAK1 flagellin receptor complex.flagellin receptor protein kinase component (FLS2)