Gene: AT5G46280

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G46280
  • Transcript Identifier AT5G46280.3
  • Gene Type Coding gene
  • Location Chr5 : 18770355-18773606 : negative

Gene Family Information

  • ID HOM05D000361
  • #Genes/#Species 1321/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G46280.3
  • symbol MCM3
  • full_name MINICHROMOSOME MAINTENANCE 3
  • uniprot Q9FL33

Descriptions

  • Description Minichromosome maintenance (MCM2/3/5) family protein
  • Computational description MINICHROMOSOME MAINTENANCE 3 (MCM3); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 3 (InterPro:IPR008046); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT4G02060.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006271
IBA
Gene OntologyDNA strand elongation involved in DNA replication1
GO:0006270
IEA
Gene OntologyDNA replication initiation
GO:0006270
IEA
InterProDNA replication initiation
GO:0032508
IEA
Gene OntologyDNA duplex unwinding
GO:0032508
IEA
InterProDNA duplex unwinding
GO:0006267
IBA
GOA Databasepre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0007049
IEA
GOA Databasecell cycle
GO:0006260
IEA
GOA DatabaseDNA replication
GO:0000727
IBA
Gene Ontologydouble-strand break repair via break-induced replication1
GO:1902975
IBA
Gene Ontologymitotic DNA replication initiation1
GO:0006268
TAS
Gene OntologyDNA unwinding involved in DNA replication2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0004386
IEA
GOA Databasehelicase activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0003678
IEA
Gene OntologyDNA helicase activity
GO:0017116
IBA
Gene Ontologysingle-stranded DNA helicase activity1
GO:0003697
IBA
Gene Ontologysingle-stranded DNA binding1
GO:0005515
IPI
Gene Ontologyprotein binding3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042555
IBA
IEA
Gene OntologyMCM complex1
GO:0042555
IEA
InterProMCM complex
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM, IBA
Gene Ontologynucleus1
GO:0000785
IDA
Gene Ontologychromatin2
GO:0000347
IDA
Gene OntologyTHO complex3

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR001208 MCM domain
IPR012340 Nucleic acid-binding, OB-fold
IPR008046 DNA replication licensing factor Mcm3
IPR031327 Mini-chromosome maintenance protein
IPR041562 MCM, AAA-lid domain
IPR033762 MCM OB domain
IPR003593 AAA+ ATPase domain
IPR027925 MCM N-terminal domain
Mapman id Description
13.2.1.2.2 Cell cycle organisation.DNA replication.preinitiation.MCM replicative DNA helicase complex.component MCM3