Gene: AT5G26780

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G26780
  • Transcript Identifier AT5G26780.4
  • Gene Type Coding gene
  • Location Chr5 : 9418299-9421725 : positive

Gene Family Information

  • ID HOM05D000575
  • #Genes/#Species 966/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G26780.4
  • symbol SHM2
  • uniprot Q94C74

Descriptions

  • Description serine hydroxymethyltransferase 2
  • Computational description serine hydroxymethyltransferase 2 (SHM2); FUNCTIONS IN: glycine hydroxymethyltransferase activity, cobalt ion binding, zinc ion binding; INVOLVED IN: glycine metabolic process, L-serine metabolic process; LOCATED IN: mitochondrion, mitochondrial respiratory chain complex I; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine transhydroxymethyltransferase 1 (TAIR:AT4G37930.1); Has 11653 Blast hits to 11631 proteins in 2851 species: Archae - 258; Bacteria - 6455; Metazoa - 332; Fungi - 287; Plants - 321; Viruses - 6; Other Eukaryotes - 3994 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046655
IBA
Gene Ontologyfolic acid metabolic process1
GO:0046653
IBA
Gene Ontologytetrahydrofolate metabolic process1
GO:0006730
IEA
GOA Databaseone-carbon metabolic process
GO:0006730
IBA
Gene Ontologyone-carbon metabolic process1
GO:0006565
IBA
Gene OntologyL-serine catabolic process1
GO:0019264
IEA
GOA Databaseglycine biosynthetic process from serine
GO:0019264
IBA
Gene Ontologyglycine biosynthetic process from serine1
GO:0019264
IEA
InterProglycine biosynthetic process from serine
GO:0035999
IEA
Gene Ontologytetrahydrofolate interconversion
GO:0035999
IEA
InterProtetrahydrofolate interconversion
GO:0006544
IDA
Gene Ontologyglycine metabolic process2
GO:0006563
IDA
Gene OntologyL-serine metabolic process2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016740
IEA
GOA Databasetransferase activity
GO:0004372
IEA
GOA Databaseglycine hydroxymethyltransferase activity
GO:0004372
IDA
IBA
Gene Ontologyglycine hydroxymethyltransferase activity1 2
GO:0004372
IEA
InterProglycine hydroxymethyltransferase activity
GO:0050897
IDA
GOA Databasecobalt ion binding
GO:0050897
HDA
IBA
Gene Ontologycobalt ion binding1 3
GO:0008270
IDA
GOA Databasezinc ion binding
GO:0008270
HDA
IBA
Gene Ontologyzinc ion binding1 3
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0030170
IEA
GOA Databasepyridoxal phosphate binding
GO:0030170
IBA
Gene Ontologypyridoxal phosphate binding1
GO:0030170
IEA
InterPropyridoxal phosphate binding
GO:0070905
IBA
Gene Ontologyserine binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
GOA Databasemitochondrion
GO:0005739
HDA
Gene Ontologymitochondrion4
GO:0005829
IDA
GOA Databasecytosol
GO:0009536
HDA
Gene Ontologyplastid5
GO:0005747
IDA
Gene Ontologymitochondrial respiratory chain complex I6
GO:0009507
ISM
Gene Ontologychloroplast
GO:0005737
IBA
Gene Ontologycytoplasm1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001085 Serine hydroxymethyltransferase
IPR015424 Pyridoxal phosphate-dependent transferase
IPR039429 Serine hydroxymethyltransferase-like domain
IPR015421 Pyridoxal phosphate-dependent transferase, major domain
IPR015422 Pyridoxal phosphate-dependent transferase, small domain
Mapman id Description
1.3.5 Photosynthesis.photorespiration.serine hydroxymethyltransferase (SHM)