Gene: AT5G22780

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G22780
  • Transcript Identifier AT5G22780.1
  • Gene Type Coding gene
  • Location Chr5 : 7590100-7597828 : negative

Gene Family Information

  • ID HOM05D000929
  • #Genes/#Species 648/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G22780.1
  • uniprot Q8LPK4

Descriptions

  • Description Adaptor protein complex AP-2, alpha subunit
  • Computational description Adaptor protein complex AP-2, alpha subunit; FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: plasma membrane; EXPRESSED IN: cultured cell; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (InterPro:IPR008152), Adaptor protein complex AP-2, alpha subunit (InterPro:IPR017104), Armadillo-like helical (InterPro:IPR011989), Clathrin adaptor, alpha-adaptin, appendage, Ig-like subdomain (InterPro:IPR013038), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553), Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain (InterPro:IPR003164), Armadillo-type fold (InterPro:IPR016024), Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain (InterPro:IPR015873), Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain (InterPro:IPR009028), Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain (InterPro:IPR013041); BEST Arabidopsis thaliana protein match is: alpha-adaptin (TAIR:AT5G22770.2); Has 2538 Blast hits to 2472 proteins in 298 species: Archae - 0; Bacteria - 2; Metazoa - 993; Fungi - 688; Plants - 265; Viruses - 0; Other Eukaryotes - 590 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0015031
IEA
GOA Databaseprotein transport
GO:0015031
IEA
InterProprotein transport
GO:0016192
IEA
GOA Databasevesicle-mediated transport
GO:0016192
IEA
InterProvesicle-mediated transport
GO:0006886
IEA
Gene Ontologyintracellular protein transport
GO:0006886
IEA
InterProintracellular protein transport
GO:0072583
IEA
GOA Databaseclathrin-dependent endocytosis
GO:0072583
IBA
Gene Ontologyclathrin-dependent endocytosis1
GO:0072583
IEA
InterProclathrin-dependent endocytosis
GO:0006897
IEA
GOA Databaseendocytosis
GO:0006898
IBA
Gene Ontologyreceptor-mediated endocytosis1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0035615
IEA
GOA Databaseclathrin adaptor activity
GO:0035615
IBA
Gene Ontologyclathrin adaptor activity1
GO:0035615
IEA
InterProclathrin adaptor activity
GO:0008289
IEA
GOA Databaselipid binding
GO:0140312
IBA
Gene Ontologycargo adaptor activity1
GO:0005515
IPI
Gene Ontologyprotein binding2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030131
IEA
GOA Databaseclathrin adaptor complex
GO:0030131
IEA
InterProclathrin adaptor complex
GO:0030117
IEA
GOA Databasemembrane coat
GO:0030117
IEA
InterPromembrane coat
GO:0030122
IEA
GOA DatabaseAP-2 adaptor complex
GO:0030122
IBA
Gene OntologyAP-2 adaptor complex1
GO:0030122
IEA
InterProAP-2 adaptor complex
GO:0005905
IEA
GOA Databaseclathrin-coated pit
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0005886
HDA
Gene Ontologyplasma membrane3
GO:0016020
IEA
GOA Databasemembrane
GO:0009536
HDA
Gene Ontologyplastid4

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR012295 TBP domain superfamily
IPR017104 Adaptor protein complex AP-2, alpha subunit
IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
IPR016024 Armadillo-type fold
IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain
IPR011989 Armadillo-like helical
IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily
IPR003164 Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain
Mapman id Description
22.3.1.3.1 Vesicle trafficking.post-Golgi trafficking.clathrin coated vesicle (CCV) machinery.AP-2 cargo adaptor complex.large subunit alpha (AP2A)