Gene: AT5G18900

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G18900
  • Transcript Identifier AT5G18900.1
  • Gene Type Coding gene
  • Location Chr5 : 6304409-6306166 : negative

Gene Family Information

  • ID HOM05D000373
  • #Genes/#Species 1301/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G18900.1
  • uniprot Q8LAN3

Descriptions

  • Description 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein
  • Computational description 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein; FUNCTIONS IN: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, L-ascorbic acid binding, iron ion binding; INVOLVED IN: oxidation reduction, peptidyl-proline hydroxylation to 4-hydroxy-L-proline; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Prolyl 4-hydroxylase, alpha subunit (InterPro:IPR006620), Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123), Metridin-like ShK toxin (InterPro:IPR003582); BEST Arabidopsis thaliana protein match is: P4H isoform 2 (TAIR:AT3G06300.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0018401
IBA
Gene Ontologypeptidyl-proline hydroxylation to 4-hydroxy-L-proline1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031418
IEA
Gene OntologyL-ascorbic acid binding
GO:0031418
IEA
InterProL-ascorbic acid binding
GO:0016705
IEA
GOA Databaseoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016705
IEA
InterProoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0005506
IEA
Gene Ontologyiron ion binding
GO:0005506
IEA
InterProiron ion binding
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0051213
IEA
GOA Databasedioxygenase activity
GO:0004656
IEA
GOA Databaseprocollagen-proline 4-dioxygenase activity
GO:0004656
IBA
Gene Ontologyprocollagen-proline 4-dioxygenase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005794
IDA
GOA DatabaseGolgi apparatus
GO:0005794
HDA
Gene OntologyGolgi apparatus2
GO:0005783
IDA
IEA
GOA Databaseendoplasmic reticulum
GO:0005783
HDA
IBA
Gene Ontologyendoplasmic reticulum1 3
GO:0016020
IEA
GOA Databasemembrane
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0005634
IDA
GOA Databasenucleus
GO:0005634
HDA
Gene Ontologynucleus4
GO:0005737
IDA
GOA Databasecytoplasm
GO:0005737
HDA
Gene Ontologycytoplasm4
GO:0005789
IEA
GOA Databaseendoplasmic reticulum membrane
GO:0000137
HDA
Gene OntologyGolgi cis cisterna5
GO:0009536
HDA
Gene Ontologyplastid6
GO:0005576
ISM
Gene Ontologyextracellular region

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR006620 Prolyl 4-hydroxylase, alpha subunit
IPR003582 ShKT domain
IPR045054 Prolyl 4-hydroxylase
IPR044862 Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
Mapman id Description
18.9.1 Protein modification.hydroxylation.prolyl hydroxylase