Gene: AT5G05980

General Information

Computational description DHFS-FPGS homolog B (DFB); CONTAINS InterPro DOMAIN/s: Folylpolyglutamate synthetase, conserved site (InterPro:IPR018109), Mur ligase, central (InterPro:IPR013221), Mur ligase, C-terminal (InterPro:IPR004101), Folylpolyglutamate synthetase (InterPro:IPR001645); BEST Arabidopsis thaliana protein match is: DHFS-FPGS homolog D (TAIR:AT3G55630.3); Has 7626 Blast hits to 7624 proteins in 2505 species: Archae - 43; Bacteria - 4775; Metazoa - 165; Fungi - 350; Plants - 132; Viruses - 0; Other Eukaryotes - 2161 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0006730	IEA	GOA Database	one-carbon metabolic process
GO:0006730	TAS	Gene Ontology	one-carbon metabolic process	1
GO:0009396	IEA	GOA Database	folic acid-containing compound biosynthetic process
GO:0009396	IBA	Gene Ontology	folic acid-containing compound biosynthetic process	2
GO:0009396	IEA	InterPro	folic acid-containing compound biosynthetic process
GO:0009058	IEA	GOA Database	biosynthetic process
GO:0009058	IEA	InterPro	biosynthetic process
GO:0046901	IMP IBA IEA	Gene Ontology	tetrahydrofolylpolyglutamate biosynthetic process	2 3
GO:0009809	IMP	Gene Ontology	lignin biosynthetic process	4
GO:1904961	IMP	Gene Ontology	quiescent center organization	3
GO:0048767	IMP	Gene Ontology	root hair elongation	3
GO:0048364	IMP	Gene Ontology	root development	3
GO:0010449	IMP	Gene Ontology	root meristem growth	3

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005524	IEA	GOA Database	ATP binding
GO:0005524	IEA	InterPro	ATP binding
GO:0004326	IEA	GOA Database	tetrahydrofolylpolyglutamate synthase activity
GO:0004326	IMP, IGI IBA	Gene Ontology	tetrahydrofolylpolyglutamate synthase activity	1 2 5
GO:0004326	IEA	InterPro	tetrahydrofolylpolyglutamate synthase activity
GO:0046872	IEA	GOA Database	metal ion binding
GO:0016874	IEA	GOA Database	ligase activity
GO:0016874	IEA	InterPro	ligase activity
GO:0000166	IEA	GOA Database	nucleotide binding

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0009507	IEA	GOA Database	chloroplast
GO:0005829	IDA	GOA Database	cytosol
GO:0005829	IBA	Gene Ontology	cytosol	2
GO:0009536	IEA	GOA Database	plastid
GO:0005737	IBA	Gene Ontology	cytoplasm	2
GO:0005739	IBA	Gene Ontology	mitochondrion	2
GO:0009570	IDA	Gene Ontology	chloroplast stroma	1

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR023600	Folylpolyglutamate synthase, eukaryota
IPR001645	Folylpolyglutamate synthetase
IPR036565	Mur-like, catalytic domain superfamily
IPR036615	Mur ligase, C-terminal domain superfamily
IPR013221	Mur ligase, central

Mapman id	Description
7.5.6	Coenzyme metabolism.tetrahydrofolate metabolism.folyl-polyglutamate synthetase