Gene: AT4G37910

General Information

Computational description mitochondrial heat shock protein 70-1 (mtHsc70-1); FUNCTIONS IN: zinc ion binding, ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to salt stress; LOCATED IN: mitochondrion, cell wall, plasma membrane, mitochondrial matrix; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Chaperone DnaK (InterPro:IPR012725), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: mitochondrial HSO70 2 (TAIR:AT5G09590.1); Has 34941 Blast hits to 34814 proteins in 4850 species: Archae - 159; Bacteria - 17270; Metazoa - 3545; Fungi - 1638; Plants - 1233; Viruses - 309; Other Eukaryotes - 10787 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0046686	IEP	GOA Database	response to cadmium ion
GO:0006457	IEA	GOA Database	protein folding
GO:0006457	TAS	Gene Ontology	protein folding	1
GO:0006457	IEA	InterPro	protein folding
GO:0009408	IEP	Gene Ontology	response to heat	1
GO:0034620	IBA	Gene Ontology	cellular response to unfolded protein	2
GO:0042026	IBA	Gene Ontology	protein refolding	2
GO:0051085	IBA	Gene Ontology	chaperone cofactor-dependent protein refolding	2

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005524	IDA IEA	GOA Database	ATP binding
GO:0005524	HDA IBA	Gene Ontology	ATP binding	2 3
GO:0005524	IEA	InterPro	ATP binding
GO:0044183	IBA	Gene Ontology	protein folding chaperone	2
GO:0008270	IDA	GOA Database	zinc ion binding
GO:0008270	HDA	Gene Ontology	zinc ion binding	4
GO:0000166	IEA	GOA Database	nucleotide binding
GO:0051082	IEA	GOA Database	unfolded protein binding
GO:0051082	IBA	Gene Ontology	unfolded protein binding	2
GO:0051082	IEA	InterPro	unfolded protein binding
GO:0016887	IBA	Gene Ontology	ATP hydrolysis activity	2
GO:0016887	IEA	InterPro	ATP hydrolysis activity
GO:0005515	IPI	Gene Ontology	protein binding	5
GO:0031072	IBA	Gene Ontology	heat shock protein binding	2
GO:0051787	IBA	Gene Ontology	misfolded protein binding	2

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005774	IDA	GOA Database	vacuolar membrane
GO:0005774	IBA	Gene Ontology	vacuolar membrane	2
GO:0005739	IDA IEA	GOA Database	mitochondrion
GO:0005739	HDA ISM, IBA	Gene Ontology	mitochondrion	2 6
GO:0005618	IDA	GOA Database	cell wall
GO:0005737	IEA	GOA Database	cytoplasm
GO:0005737	IBA	Gene Ontology	cytoplasm	2
GO:0005794	RCA	Gene Ontology	Golgi apparatus	7
GO:0005759	TAS	Gene Ontology	mitochondrial matrix	1
GO:0009505	HDA	Gene Ontology	plant-type cell wall	8
GO:0000325	HDA	Gene Ontology	plant-type vacuole	9
GO:0005829	HDA RCA	Gene Ontology	cytosol	10 11
GO:0005886	HDA	Gene Ontology	plasma membrane	12

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR043129	ATPase, nucleotide binding domain
IPR012725	Chaperone DnaK
IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily
IPR029048	Heat shock protein 70kD, C-terminal domain superfamily
IPR013126	Heat shock protein 70 family

Mapman id	Description
19.1.3.1	Protein homeostasis.protein quality control.mitochondrial Hsp70 chaperone system.chaperone (mtHsc70)
7.11.2.2.5	Coenzyme metabolism.iron-sulfur cluster assembly machinery.mitochondrial ISC system.transfer phase.chaperone (HSCA)