Gene: AT4G37270

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G37270
  • Transcript Identifier AT4G37270.1
  • Gene Type Coding gene
  • Location Chr4 : 17541987-17546352 : negative

Gene Family Information

  • ID HOM05D000343
  • #Genes/#Species 1379/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G37270.1
  • symbol HMA1
  • Alias ATHMA1,ARABIDOPSIS THALIANA HEAVY METAL ATPASE 1
  • uniprot Q9M3H5

Descriptions

  • Description heavy metal atpase 1
  • Computational description heavy metal atpase 1 (HMA1); FUNCTIONS IN: copper-exporting ATPase activity, ATPase activity, calcium-transporting ATPase activity, zinc transporting ATPase activity, cadmium-transporting ATPase activity; INVOLVED IN: cellular copper ion homeostasis, calcium ion transport, response to toxin, zinc ion homeostasis, response to light intensity; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating (InterPro:IPR006404), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: heavy metal atpase 2 (TAIR:AT4G30110.1); Has 36740 Blast hits to 31592 proteins in 3081 species: Archae - 714; Bacteria - 24289; Metazoa - 3807; Fungi - 1794; Plants - 1612; Viruses - 8; Other Eukaryotes - 4516 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006812
IEA
GOA Databasecation transport
GO:0006812
IEA
InterProcation transport
GO:0009636
IGI
Gene Ontologyresponse to toxic substance1
GO:0006878
IMP
Gene Ontologycellular copper ion homeostasis2
GO:0009642
IMP
Gene Ontologyresponse to light intensity2
GO:0006816
IGI
Gene Ontologycalcium ion transport1
GO:0055069
IMP
Gene Ontologyzinc ion homeostasis3
GO:0098655
IEA
GOA Databasecation transmembrane transport
GO:0070574
IEA
GOA Databasecadmium ion transmembrane transport
GO:0034220
IEA
GOA Databaseion transmembrane transport
GO:0000041
IEA
GOA Databasetransition metal ion transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0000166
IEA
InterPronucleotide binding
GO:0016463
IEA
GOA DatabaseP-type zinc transporter activity
GO:0016463
IDA
Gene OntologyP-type zinc transporter activity3
GO:0019829
IEA
GOA DatabaseATPase-coupled cation transmembrane transporter activity
GO:0019829
IEA
InterProATPase-coupled cation transmembrane transporter activity
GO:0005215
IEA
InterProtransporter activity
GO:0016887
IMP
Gene OntologyATP hydrolysis activity2
GO:0016887
IEA
InterProATP hydrolysis activity
GO:0043682
ISS
Gene OntologyP-type divalent copper transporter activity
GO:0005388
IGI
Gene OntologyP-type calcium transporter activity1
GO:0008551
IGI
IEA
Gene OntologyP-type cadmium transporter activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009706
IEA
GOA Databasechloroplast inner membrane
GO:0009536
IDA
IEA
GOA Databaseplastid
GO:0009536
HDA
Gene Ontologyplastid4
GO:0009507
IDA
IEA
GOA Databasechloroplast
GO:0009507
HDA
ISM
Gene Ontologychloroplast5
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0016021
IEA
InterProintegral component of membrane
GO:0016020
IEA
GOA Databasemembrane
GO:0009528
IEA
GOA Databaseplastid inner membrane
GO:0009941
IDA, HDA
Gene Ontologychloroplast envelope2 6
GO:0005886
HDA
Gene Ontologyplasma membrane7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036412 HAD-like superfamily
IPR023298 P-type ATPase, transmembrane domain superfamily
IPR023299 P-type ATPase, cytoplasmic domain N
IPR023214 HAD superfamily
IPR001757 P-type ATPase
IPR027256 P-type ATPase, subfamily IB
IPR008250 P-type ATPase, A domain superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domain
Mapman id Description
24.1.2.1.1 Solute transport.primary active transport.P-type ATPase superfamily.P1 family.P1B-type heavy metal cation-transporting ATPase (HMA)