Gene: AT4G35830

General Information

Computational description aconitase 1 (ACO1); FUNCTIONS IN: aconitate hydratase activity, copper ion binding, mRNA 5'-UTR binding; INVOLVED IN: response to salt stress, isocitrate metabolic process, citrate metabolic process; LOCATED IN: cytosol, mitochondrion, apoplast, plasma membrane, vacuole; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Aconitase family, 4Fe-4S cluster binding site (InterPro:IPR018136), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha (InterPro:IPR001030), Aconitase A/isopropylmalate dehydratase small subunit, swivel (InterPro:IPR000573), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 (InterPro:IPR015932), Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase (InterPro:IPR015934), Aconitase/3-isopropylmalate dehydratase, swivel (InterPro:IPR015928), Aconitase-like core (InterPro:IPR015937), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (InterPro:IPR015931), Aconitase/iron regulatory protein 2 (InterPro:IPR006249); BEST Arabidopsis thaliana protein match is: aconitase 3 (TAIR:AT2G05710.1); Has 20862 Blast hits to 20684 proteins in 2607 species: Archae - 544; Bacteria - 10896; Metazoa - 494; Fungi - 666; Plants - 229; Viruses - 0; Other Eukaryotes - 8033 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0006099	IBA IEA	Gene Ontology	tricarboxylic acid cycle	1
GO:0006101	IMP IBA	Gene Ontology	citrate metabolic process	1 2
GO:0006102	IMP	Gene Ontology	isocitrate metabolic process	2
GO:1990641	IEP	Gene Ontology	response to iron ion starvation	3

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0051539	IEA	GOA Database	4 iron, 4 sulfur cluster binding
GO:0051539	IBA	Gene Ontology	4 iron, 4 sulfur cluster binding	1
GO:0003994	IMP IBA IEA	Gene Ontology	aconitate hydratase activity	1 2
GO:0005507	IDA	GOA Database	copper ion binding
GO:0005507	HDA	Gene Ontology	copper ion binding	4
GO:0051536	IEA	GOA Database	iron-sulfur cluster binding
GO:0046872	IEA	GOA Database	metal ion binding
GO:0016829	IEA	GOA Database	lyase activity
GO:0047780	IEA	Gene Ontology	citrate dehydratase activity
GO:0048027	IDA	Gene Ontology	mRNA 5'-UTR binding	2

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005739	IDA IEA	GOA Database	mitochondrion
GO:0005739	HDA IBA	Gene Ontology	mitochondrion	1 5
GO:0005829	IDA	GOA Database	cytosol
GO:0005829	HDA IBA NAS	Gene Ontology	cytosol	1 2 6
GO:0005737	IEA	GOA Database	cytoplasm
GO:0005737	ISM	Gene Ontology	cytoplasm
GO:0005773	IDA	GOA Database	vacuole
GO:0005886	IDA	GOA Database	plasma membrane
GO:0005886	HDA	Gene Ontology	plasma membrane	7
GO:0048046	IDA	GOA Database	apoplast
GO:0048046	HDA	Gene Ontology	apoplast	8
GO:0009506	IDA	GOA Database	plasmodesma
GO:0009506	HDA	Gene Ontology	plasmodesma	9
GO:0000325	HDA	Gene Ontology	plant-type vacuole	10

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR001030	Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
IPR036008	Aconitase, iron-sulfur domain
IPR006249	Aconitase/Iron-responsive element-binding protein 2
IPR015931	Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
IPR044137	Aconitase A, swivel domain
IPR015928	Aconitase/3-isopropylmalate dehydratase, swivel
IPR000573	Aconitase A/isopropylmalate dehydratase small subunit, swivel domain

Mapman id	Description
2.3.2	Cellular respiration.tricarboxylic acid cycle.aconitase
5.7.3.6.2	Lipid metabolism.lipid degradation.fatty acid degradation.glyoxylate cycle.aconitase