Gene: AT4G34890
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT4G34890
- Transcript Identifier AT4G34890.1
- Gene Type Coding gene
- Location Chr4 : 16618736-16624983 : negative
Gene Family Information
- ID HOM05D001013
- #Genes/#Species 597/100
- Phylogenetic origin
- ID ORTHO05D004597
- #Genes/#Species 176/97
- Phylogenetic origin
Gene Duplication Information
- Tandem Duplication Tandem duplicate
Labels
Identifiers
- tid AT4G34890.1
- symbol XDH1
- Alias ATXDH1,XANTHINE DEHYDROGENASE 1
- uniprot Q8GUQ8
Descriptions
- Description xanthine dehydrogenase 1
- Computational description xanthine dehydrogenase 1 (XDH1); CONTAINS InterPro DOMAIN/s: Aldehyde oxidase/xanthine dehydrogenase (InterPro:IPR016208), Ferredoxin (InterPro:IPR001041), Molybdopterin dehydrogenase, FAD-binding (InterPro:IPR002346), [2Fe-2S]-binding (InterPro:IPR002888), FAD-binding, type 2, subdomain 1 (InterPro:IPR016167), FAD-binding, type 2 (InterPro:IPR016166), CO dehydrogenase flavoprotein, C-terminal (InterPro:IPR005107), 2Fe-2S ferredoxin, iron-sulphur binding site (InterPro:IPR006058), CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 (InterPro:IPR016169), Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (InterPro:IPR000674), Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding (InterPro:IPR008274); BEST Arabidopsis thaliana protein match is: xanthine dehydrogenase 2 (TAIR:AT4G34900.1); Has 21952 Blast hits to 20911 proteins in 1336 species: Archae - 451; Bacteria - 13165; Metazoa - 1072; Fungi - 101; Plants - 265; Viruses - 0; Other Eukaryotes - 6898 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0009414 | IMP | Gene Ontology | response to water deprivation | 1 |
| GO:0000302 | IMP | Gene Ontology | response to reactive oxygen species | 1 |
| GO:0006145 | IMP TAS | Gene Ontology | purine nucleobase catabolic process | 2 3 |
| GO:0046110 | IMP | Gene Ontology | xanthine metabolic process | 4 |
| GO:0042554 | IMP | Gene Ontology | superoxide anion generation | 5 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0004854 | IEA | GOA Database | xanthine dehydrogenase activity | |
| GO:0004854 | IDA | Gene Ontology | xanthine dehydrogenase activity | 2 |
| GO:0005506 | IEA | Gene Ontology | iron ion binding | |
| GO:0005506 | IEA | InterPro | iron ion binding | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0046872 | IEA | InterPro | metal ion binding | |
| GO:0050660 | IEA | GOA Database | flavin adenine dinucleotide binding | |
| GO:0050660 | IEA | InterPro | flavin adenine dinucleotide binding | |
| GO:0051536 | IEA | GOA Database | iron-sulfur cluster binding | |
| GO:0051536 | IEA | InterPro | iron-sulfur cluster binding | |
| GO:0016491 | IEA | GOA Database | oxidoreductase activity | |
| GO:0016491 | IBA | Gene Ontology | oxidoreductase activity | 6 |
| GO:0016491 | IEA | InterPro | oxidoreductase activity | |
| GO:0051537 | IEA | GOA Database | 2 iron, 2 sulfur cluster binding | |
| GO:0071949 | IEA | Gene Ontology | FAD binding |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005829 | IDA | GOA Database | cytosol | |
| GO:0005886 | HDA | Gene Ontology | plasma membrane | 7 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR036856 | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily |
| IPR000674 | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead |
| IPR016167 | FAD-binding, type PCMH, subdomain 1 |
| IPR036683 | CO dehydrogenase flavoprotein, C-terminal domain superfamily |
| IPR037165 | Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily |
| IPR001041 | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
| IPR016169 | FAD-binding, type PCMH, subdomain 2 |
| IPR002346 | Molybdopterin dehydrogenase, FAD-binding |
| IPR036318 | FAD-binding, type PCMH-like superfamily |
| IPR002888 | [2Fe-2S]-binding |
| IPR005107 | CO dehydrogenase flavoprotein, C-terminal |
| IPR008274 | Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding |
| IPR016208 | Aldehyde oxidase/xanthine dehydrogenase |
| IPR036884 | [2Fe-2S]-binding domain superfamily |
| IPR012675 | Beta-grasp domain superfamily |
| IPR036010 | 2Fe-2S ferredoxin-like superfamily |