Gene: AT4G33520
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT4G33520
- Transcript Identifier AT4G33520.2
- Gene Type Coding gene
- Location Chr4 : 16118993-16125849 : positive
Gene Family Information
- ID HOM05D000343
- #Genes/#Species 1379/99
- Phylogenetic origin
- ID ORTHO05D002777
- #Genes/#Species 262/97
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT4G33520.2
- symbol PAA1
- Alias AtHMAC6,Arabidopsis thaliana heavy metal ATPase 6,HMA6,HEAVY METAL ATPASE 6
- uniprot Q9SZC9
Descriptions
- Description P-type ATP-ase 1
- Computational description P-type ATP-ase 1 (PAA1); FUNCTIONS IN: copper ion transmembrane transporter activity, ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: photosynthetic electron transport chain; LOCATED IN: chloroplast, chloroplast stroma, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), Heavy-metal-associated, conserved site (InterPro:IPR017969); BEST Arabidopsis thaliana protein match is: P-type ATPase of Arabidopsis 2 (TAIR:AT5G21930.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
- Computational description P-type ATP-ase 1 (PAA1); FUNCTIONS IN: copper ion transmembrane transporter activity, ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: photosynthetic electron transport chain; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type copper-transporter (InterPro:IPR001756), Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P type, cation/copper-transporter (InterPro:IPR006403), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), Heavy-metal-associated, conserved site (InterPro:IPR017969), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: P-type ATPase of Arabidopsis 2 (TAIR:AT5G21930.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
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Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006825 | IEA | GOA Database | copper ion transport | |
| GO:0006812 | IEA | GOA Database | cation transport | |
| GO:0006812 | IEA | InterPro | cation transport | |
| GO:0006811 | IEA | GOA Database | ion transport | |
| GO:0009767 | IMP | Gene Ontology | photosynthetic electron transport chain | 1 |
| GO:0035434 | IMP | Gene Ontology | copper ion transmembrane transport | 1 |
| GO:0055070 | IDA | Gene Ontology | copper ion homeostasis | 2 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0043682 | IBA | GOA Database | P-type divalent copper transporter activity | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0046872 | IEA | InterPro | metal ion binding | |
| GO:0000166 | IEA | GOA Database | nucleotide binding | |
| GO:0000166 | IEA | InterPro | nucleotide binding | |
| GO:0005524 | IEA | GOA Database | ATP binding | |
| GO:0005524 | IEA | InterPro | ATP binding | |
| GO:0019829 | IEA | Gene Ontology | ATPase-coupled cation transmembrane transporter activity | |
| GO:0019829 | IEA | InterPro | ATPase-coupled cation transmembrane transporter activity | |
| GO:0005215 | IEA | InterPro | transporter activity | |
| GO:0016887 | IEA | InterPro | ATP hydrolysis activity | |
| GO:0016531 | IDA | Gene Ontology | copper chaperone activity | 2 |
| GO:0140581 | IEA | Gene Ontology | P-type monovalent copper transporter activity | |
| GO:0005375 | IMP | Gene Ontology | copper ion transmembrane transporter activity | 3 |
| GO:0015662 | ISS | Gene Ontology | P-type ion transporter activity | |
| GO:0005515 | IPI | Gene Ontology | protein binding | 4 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0009507 | IDA IEA | GOA Database | chloroplast | |
| GO:0009507 | HDA | Gene Ontology | chloroplast | 5 |
| GO:0016021 | IEA | GOA Database | integral component of membrane | |
| GO:0016021 | IEA | InterPro | integral component of membrane | |
| GO:0016020 | IEA | GOA Database | membrane | |
| GO:0009941 | IDA | Gene Ontology | chloroplast envelope | 3 |
| GO:0009536 | IDA IEA | GOA Database | plastid | |
| GO:0009536 | HDA | Gene Ontology | plastid | 6 |
| GO:0005886 | HDA | Gene Ontology | plasma membrane | 7 |
| GO:0031969 | IEA | GOA Database | chloroplast membrane | |
| GO:0009570 | IDA | GOA Database | chloroplast stroma |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR023298 | P-type ATPase, transmembrane domain superfamily |
| IPR008250 | P-type ATPase, A domain superfamily |
| IPR027256 | P-type ATPase, subfamily IB |
| IPR023299 | P-type ATPase, cytoplasmic domain N |
| IPR023214 | HAD superfamily |
| IPR006121 | Heavy metal-associated domain, HMA |
| IPR036163 | Heavy metal-associated domain superfamily |
| IPR036412 | HAD-like superfamily |
| IPR001757 | P-type ATPase |
| IPR044492 | P-type ATPase, haloacid dehalogenase domain |
| Mapman id | Description |
|---|---|
| 24.1.2.1.1 | Solute transport.primary active transport.P-type ATPase superfamily.P1 family.P1B-type heavy metal cation-transporting ATPase (HMA) |