Gene: AT4G29040

General Information

Computational description regulatory particle AAA-ATPase 2A (RPT2a); FUNCTIONS IN: ATPase activity; INVOLVED IN: in 17 processes; LOCATED IN: proteasome regulatory particle, base subcomplex, proteasome complex, nucleus, membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), 26S proteasome subunit P45 (InterPro:IPR005937); BEST Arabidopsis thaliana protein match is: AAA-type ATPase family protein (TAIR:AT2G20140.1); Has 31112 Blast hits to 28760 proteins in 3112 species: Archae - 1431; Bacteria - 10308; Metazoa - 4877; Fungi - 3744; Plants - 3214; Viruses - 41; Other Eukaryotes - 7497 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0060968	IMP	Gene Ontology	regulation of gene silencing	1
GO:0043161	IMP IBA	Gene Ontology	proteasome-mediated ubiquitin-dependent protein catabolic process	2 3
GO:1901800	IEA	GOA Database	positive regulation of proteasomal protein catabolic process
GO:0046686	IEP	GOA Database	response to cadmium ion
GO:0045087	IEA	GOA Database	innate immune response
GO:0045087	IMP	Gene Ontology	innate immune response	4
GO:0002376	IEA	GOA Database	immune system process
GO:0030163	IEA	GOA Database	protein catabolic process
GO:0030163	IEA	InterPro	protein catabolic process
GO:0048829	IMP	Gene Ontology	root cap development	5
GO:0006511	TAS	Gene Ontology	ubiquitin-dependent protein catabolic process	6
GO:0009933	IMP	Gene Ontology	meristem structural organization	5
GO:0009965	IMP	Gene Ontology	leaf morphogenesis	5
GO:0010015	IMP	Gene Ontology	root morphogenesis	5
GO:0010078	IMP	Gene Ontology	maintenance of root meristem identity	5
GO:0010311	IMP	Gene Ontology	lateral root formation	5
GO:0035266	IMP	Gene Ontology	meristem growth	5
GO:0048367	IMP	Gene Ontology	shoot system development	5
GO:0048827	IMP	Gene Ontology	phyllome development	5
GO:0009408	IMP	Gene Ontology	response to heat	2
GO:0043248	IMP	Gene Ontology	proteasome assembly	2
GO:0048364	IMP	Gene Ontology	root development	2
GO:0051788	IMP	Gene Ontology	response to misfolded protein	2
GO:0080129	IMP	Gene Ontology	proteasome core complex assembly	2
GO:0007292	IGI	Gene Ontology	female gamete generation	7
GO:0048232	IGI	Gene Ontology	male gamete generation	7
GO:0090351	IMP	Gene Ontology	seedling development	8

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0000166	IEA	GOA Database	nucleotide binding
GO:0036402	IEA	GOA Database	proteasome-activating activity
GO:0036402	IBA	Gene Ontology	proteasome-activating activity	3
GO:0036402	IEA	InterPro	proteasome-activating activity
GO:0005524	IEA	GOA Database	ATP binding
GO:0005524	IEA	InterPro	ATP binding
GO:0017025	IBA	GOA Database	TBP-class protein binding
GO:0016887	IGI	Gene Ontology	ATP hydrolysis activity	9
GO:0016887	IEA	InterPro	ATP hydrolysis activity

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005886	HDA	Gene Ontology	plasma membrane	10
GO:0008540	IDA IBA	Gene Ontology	proteasome regulatory particle, base subcomplex	3 11
GO:0005634	IEA	GOA Database	nucleus
GO:0005634	ISM TAS	Gene Ontology	nucleus	12
GO:0000932	IEA	GOA Database	P-body
GO:0000502	IEA	GOA Database	proteasome complex
GO:0000502	IDA	Gene Ontology	proteasome complex	13
GO:0005737	IEA	GOA Database	cytoplasm
GO:0005737	IEA	InterPro	cytoplasm
GO:0005829	RCA	Gene Ontology	cytosol	14

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR003959	ATPase, AAA-type, core
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR041569	AAA ATPase, AAA+ lid domain
IPR032501	Proteasomal ATPase OB C-terminal domain
IPR005937	26S proteasome regulatory subunit P45-like
IPR003593	AAA+ ATPase domain

Mapman id	Description
19.2.5.2.1.2	Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT2