Gene: AT4G21810

General Information

Structural Information

Species Arabidopsis thaliana
Gene Identifier AT4G21810
Transcript Identifier AT4G21810.1
Gene Type Coding gene
Location Chr4 : 11575345-11577003 : negative

Gene Family Information

Homologous GF
Orthologous GF

ID HOM05D001731
#Genes/#Species 374/99
Phylogenetic origin

ID ORTHO05D004784
#Genes/#Species 171/99
Phylogenetic origin

Gene Duplication Information

Block Duplication Block duplicate

Labels

Identifiers

tid AT4G21810.1
symbol DER2.1
uniprot Q8VZ96

Descriptions

Description DERLIN-2.1

Computational description DERLIN-2.1 (DER2.1); CONTAINS InterPro DOMAIN/s: Der1-like (InterPro:IPR007599); BEST Arabidopsis thaliana protein match is: DERLIN-2.2 (TAIR:AT4G04860.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

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Functional Annotation

Biological Process

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0030433	IBA	Gene Ontology	ubiquitin-dependent ERAD pathway	1
GO:0030968	IBA	Gene Ontology	endoplasmic reticulum unfolded protein response	1

Molecular Function

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:1990381	IBA	Gene Ontology	ubiquitin-specific protease binding	1
GO:0051787	IBA	Gene Ontology	misfolded protein binding	1

Cellular Component

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0030176	IBA	Gene Ontology	integral component of endoplasmic reticulum membrane	1
GO:0000839	IBA	Gene Ontology	Hrd1p ubiquitin ligase ERAD-L complex	1
GO:0005789	IEA	GOA Database	endoplasmic reticulum membrane
GO:0016021	IEA	GOA Database	integral component of membrane
GO:0016020	IEA	GOA Database	membrane
GO:0005783	IEA	GOA Database	endoplasmic reticulum

Color Legend

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR007599	Derlin
IPR035952	Rhomboid-like superfamily

Mapman id	Description
19.2.4.2.2.2	Protein homeostasis.ubiquitin-proteasome system.membrane-associated protein degradation.ER-associated protein degradation (ERAD).substrate extraction.membrane protein retrotranslocase (DFM1)