Gene: AT4G19710

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G19710
  • Transcript Identifier AT4G19710.2
  • Gene Type Coding gene
  • Location Chr4 : 10725229-10729536 : positive

Gene Family Information

  • ID HOM05D001813
  • #Genes/#Species 361/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G19710.2
  • symbol AK-HSDH II
  • Alias AK-HSDH,ASPARTATE KINASE-HOMOSERINE DEHYDROGENASE
  • uniprot O81852

Descriptions

  • Description aspartate kinase-homoserine dehydrogenase ii
  • Computational description aspartate kinase-homoserine dehydrogenase ii (AK-HSDH II); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Homoserine dehydrogenase, catalytic (InterPro:IPR001342), Amino acid-binding ACT (InterPro:IPR002912), Aspartate/homoserine dehydrogenase, NAD-binding (InterPro:IPR005106), Aspartate kinase, conserved site (InterPro:IPR018042), Bifunctional aspartokinase/homoserine dehydrogenase I (InterPro:IPR011147), Aspartate kinase domain (InterPro:IPR001341), NAD(P)-binding domain (InterPro:IPR016040), Homoserine dehydrogenase, conserved site (InterPro:IPR019811); BEST Arabidopsis thaliana protein match is: aspartate kinase-homoserine dehydrogenase i (TAIR:AT1G31230.1); Has 17435 Blast hits to 17108 proteins in 2575 species: Archae - 421; Bacteria - 11654; Metazoa - 7; Fungi - 299; Plants - 259; Viruses - 0; Other Eukaryotes - 4795 (source: NCBI BLink).
  • Computational description aspartate kinase-homoserine dehydrogenase ii (AK-HSDH II); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Homoserine dehydrogenase, catalytic (InterPro:IPR001342), Amino acid-binding ACT (InterPro:IPR002912), Aspartate/homoserine dehydrogenase, NAD-binding (InterPro:IPR005106), Aspartate kinase, conserved site (InterPro:IPR018042), NAD(P)-binding domain (InterPro:IPR016040), Aspartate kinase domain (InterPro:IPR001341), Bifunctional aspartokinase/homoserine dehydrogenase I (InterPro:IPR011147), Homoserine dehydrogenase, conserved site (InterPro:IPR019811); BEST Arabidopsis thaliana protein match is: aspartate kinase-homoserine dehydrogenase i (TAIR:AT1G31230.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006520
IEA
GOA Databasecellular amino acid metabolic process
GO:0006520
IEA
InterProcellular amino acid metabolic process
GO:0008652
IEA
GOA Databasecellular amino acid biosynthetic process
GO:0008652
IEA
InterProcellular amino acid biosynthetic process
GO:0009086
IEA
GOA Databasemethionine biosynthetic process
GO:0016310
IEA
GOA Databasephosphorylation
GO:0008152
IEA
GOA Databasemetabolic process
GO:0009067
IEA
GOA Databaseaspartate family amino acid biosynthetic process
GO:0009067
IBA
TAS
Gene Ontologyaspartate family amino acid biosynthetic process1 2
GO:0009067
IEA
InterProaspartate family amino acid biosynthetic process
GO:0009090
IBA
Gene Ontologyhomoserine biosynthetic process2
GO:0009089
IEA
Gene Ontologylysine biosynthetic process via diaminopimelate
GO:0009088
IEA
Gene Ontologythreonine biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016740
IEA
GOA Databasetransferase activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0016301
IEA
GOA Databasekinase activity
GO:0004072
IEA
GOA Databaseaspartate kinase activity
GO:0004072
IDA
Gene Ontologyaspartate kinase activity3
GO:0004072
IEA
InterProaspartate kinase activity
GO:0050661
IEA
Gene OntologyNADP binding
GO:0050661
IEA
InterProNADP binding
GO:0004412
IEA
GOA Databasehomoserine dehydrogenase activity
GO:0004412
IDA
IBA
Gene Ontologyhomoserine dehydrogenase activity2 3
GO:0004412
IEA
InterProhomoserine dehydrogenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IDA
IEA
GOA Databasechloroplast
GO:0009507
HDA
ISM
Gene Ontologychloroplast4
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma5
GO:0009536
IEA
GOA Databaseplastid

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001341 Aspartate kinase
IPR027795 CASTOR, ACT domain
IPR001048 Aspartate/glutamate/uridylate kinase
IPR002912 ACT domain
IPR036291 NAD(P)-binding domain superfamily
IPR041743 Bifunctional aspartokinase/homoserine dehydrogenase, N-terminal catalytic domain
IPR036393 Acetylglutamate kinase-like superfamily
IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding
IPR001342 Homoserine dehydrogenase, catalytic
IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I
Mapman id Description
4.1.2.2.4 Amino acid metabolism.biosynthesis.aspartate family.aspartate-derived amino acids.bifunctional homoserine dehydrogenase and aspartate kinase