Gene: AT4G11820

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G11820
  • Transcript Identifier AT4G11820.3
  • Gene Type Coding gene
  • Location Chr4 : 7109124-7111213 : negative

Gene Family Information

  • ID HOM05D002871
  • #Genes/#Species 241/96
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G11820.3
  • symbol HMGS
  • Alias FKP1,FLAKY POLLEN 1,MVA1
  • full_name HYDROXYMETHYLGLUTARYL-COA SYNTHASE
  • uniprot P54873

Descriptions

  • Description hydroxymethylglutaryl-CoA synthase / HMG-CoA synthase / 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • Computational description HYDROXYMETHYLGLUTARYL-COA SYNTHASE (HMGS); CONTAINS InterPro DOMAIN/s: Hydroxymethylglutaryl-coenzyme A synthase C-terminal (InterPro:IPR013746), Thiolase-like (InterPro:IPR016039), Hydroxymethylglutaryl-coenzyme A synthase, N-terminal (InterPro:IPR013528), Hydroxymethylglutaryl-CoA synthase, eukaryotic (InterPro:IPR010122), Hydroxymethylglutaryl-coenzyme A synthase, active site (InterPro:IPR000590); Has 2141 Blast hits to 2138 proteins in 847 species: Archae - 222; Bacteria - 1037; Metazoa - 301; Fungi - 182; Plants - 116; Viruses - 0; Other Eukaryotes - 283 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006694
IEA
GOA Databasesteroid biosynthetic process
GO:0010142
IEA
GOA Databasefarnesyl diphosphate biosynthetic process, mevalonate pathway
GO:0010142
IBA
Gene Ontologyfarnesyl diphosphate biosynthetic process, mevalonate pathway1
GO:0010142
IEA
InterProfarnesyl diphosphate biosynthetic process, mevalonate pathway
GO:0006084
IEA
GOA Databaseacetyl-CoA metabolic process
GO:0006084
IBA
Gene Ontologyacetyl-CoA metabolic process1
GO:0006084
IEA
InterProacetyl-CoA metabolic process
GO:0008299
IEA
GOA Databaseisoprenoid biosynthetic process
GO:0008299
IEA
InterProisoprenoid biosynthetic process
GO:0016126
IEA
GOA Databasesterol biosynthetic process
GO:0008202
IEA
GOA Databasesteroid metabolic process
GO:0006629
IEA
GOA Databaselipid metabolic process
GO:0019287
TAS
Gene Ontologyisopentenyl diphosphate biosynthetic process, mevalonate pathway2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004421
IEA
GOA Databasehydroxymethylglutaryl-CoA synthase activity
GO:0004421
IGI
ISS, IBA
Gene Ontologyhydroxymethylglutaryl-CoA synthase activity1 3
GO:0004421
IEA
InterProhydroxymethylglutaryl-CoA synthase activity
GO:0016746
IEA
GOA Databaseacyltransferase activity
GO:0016746
IEA
InterProacyltransferase activity
GO:0016740
IEA
GOA Databasetransferase activity
GO:0003985
IGI
Gene Ontologyacetyl-CoA C-acetyltransferase activity3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
ISM
Gene Ontologymitochondrion
GO:0009506
IDA
GOA Databaseplasmodesma
GO:0009506
HDA
Gene Ontologyplasmodesma4
GO:0005829
IDA
GOA Databasecytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
IPR016039 Thiolase-like
IPR010122 Hydroxymethylglutaryl-CoA synthase, eukaryotic
IPR013746 Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain
Mapman id Description
9.1.1.2 Secondary metabolism.terpenoids.mevalonate pathway.3-hydroxy-3-methylglutaryl-CoA synthase