Gene: AT4G08500

General Information

Computational description MAPK/ERK kinase kinase 1 (MEKK1); FUNCTIONS IN: protein binding, kinase binding, DNA binding, MAP kinase kinase kinase activity, kinase activity; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 9 (TAIR:AT4G08480.1); Has 132336 Blast hits to 130259 proteins in 4567 species: Archae - 142; Bacteria - 14700; Metazoa - 49430; Fungi - 12971; Plants - 32949; Viruses - 685; Other Eukaryotes - 21459 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0000165	IPI, IMP	Gene Ontology	MAPK cascade	1
GO:0046777	IDA	GOA Database	protein autophosphorylation
GO:0046777	HDA	Gene Ontology	protein autophosphorylation	2
GO:0006952	IEA	GOA Database	defense response
GO:0045087	IEA	GOA Database	innate immune response
GO:0016310	IEA	GOA Database	phosphorylation
GO:0002376	IEA	GOA Database	immune system process
GO:0006468	IEA	GOA Database	protein phosphorylation
GO:0006468	IEA	InterPro	protein phosphorylation
GO:0010200	ISO	PLAZA Integrative Orthology	response to chitin	Pp3c7_4010
GO:0046686	IGI	Gene Ontology	response to cadmium ion
GO:0006970	IGI, IEP	Gene Ontology	response to osmotic stress	3
GO:0009651	IEP	Gene Ontology	response to salt stress	3
GO:0009611	IDA	Gene Ontology	response to wounding	4
GO:0010449	IGI	Gene Ontology	root meristem growth	5
GO:0022622	IMP	Gene Ontology	root system development	5
GO:1902065	IMP	Gene Ontology	response to L-glutamate	5
GO:0009409	IDA, IEP	Gene Ontology	response to cold	6 7
GO:0009631	IDA	Gene Ontology	cold acclimation	7

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0004674	IEA	GOA Database	protein serine/threonine kinase activity
GO:0004674	IDA, HDA	Gene Ontology	protein serine/threonine kinase activity	2 7
GO:0106311	IEA	GOA Database	protein threonine kinase activity
GO:0106310	IEA	GOA Database	protein serine kinase activity
GO:0004709	IEA	GOA Database	MAP kinase kinase kinase activity
GO:0004709	IDA ISS	Gene Ontology	MAP kinase kinase kinase activity	4 6
GO:0000166	IEA	GOA Database	nucleotide binding
GO:0016740	IEA	GOA Database	transferase activity
GO:0005524	IEA	GOA Database	ATP binding
GO:0005524	IEA	InterPro	ATP binding
GO:0016301	IEA	GOA Database	kinase activity
GO:0004672	IEA	GOA Database	protein kinase activity
GO:0004672	IEA	InterPro	protein kinase activity
GO:0005515	IPI	Gene Ontology	protein binding	4
GO:0003677	IDA	Gene Ontology	DNA binding	8
GO:0019900	IPI	Gene Ontology	kinase binding	8

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005886	IEA	GOA Database	plasma membrane
GO:0005886	IDA	Gene Ontology	plasma membrane	9
GO:0005768	IEA	GOA Database	endosome
GO:0005768	IDA	Gene Ontology	endosome	9
GO:0016020	IEA	GOA Database	membrane
GO:0005634	IDA ISM	Gene Ontology	nucleus	8

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR000719	Protein kinase domain
IPR011009	Protein kinase-like domain superfamily

Mapman id	Description
18.4.2.2	Protein modification.phosphorylation.STE protein kinase superfamily.protein kinase (MAP3K-MEKK)